World Stroke Organization #MondayTips
Every Monday, WSA Social Media Leader Rodrigo Guerrero publishes a #MondayTip on the WSA WorldStrokeEd Twitter account, covering a specific stroke related topic. You can find a compilation of our #MondayTips here!
May #PaperofTheMonth: πππππππ-ππππππ: π
ππππ¨π« πππ ππ§π‘π’ππ’ππ’π¨π§ ππππ©π¬ π’π§ππ¨ ππππ¨π§πππ«π² πππ«π¨π€π ππ«ππ―ππ§ππ’π¨π§
π€Commentary
π½#MondayTip
π§4 expert interview episodes
Access it: https://www.world-stroke-academy.org/news/the-paper-of-the-month-may-4/
#StrokeEducation
#MondayTip
#TRIDENT
πOne pill could change post-ICH care.
π§ Low-dose triple antihypertensive therapy β recurrent stroke by 39% and improved BP control vs standard care
βοΈSimpler regimens may beat therapeutic inertia
πhttps://doi.org/10.1056/nejmoa2515043
#MondayTip
#Tenecteplase may helpβeven when the artery stays closed.
In #TRACE3 (4.5β24h window), pts without recanalization still had better outcomes (42% vs 30%). Strongest effect in NIHSS β₯10.
π Think beyond large vessel reopening
https://doi.org/10.1186/s12916-026-04877-x
#MondayTip
Can we prevent stroke without increasing bleeding?
Factor XIa inhibition #asundexian :
πΉβ¬οΈrecurrent stroke (HR 0.74)
πΈwith no β¬οΈmajor bleeding in OCEANIC-STROKE.
A potential shift in secondary prevention. π§ βοΈ
π https://www.nejm.org/doi/full/10.1056/NEJMoa2513880
#MondayTip
#GFAP
πRises early in intracerebral hemorrhage (2β6h)π©Έ, but later in ischemic stroke (peak days 2β5)
π‘Promising for early differentiation & triage
βοΈbut not ready as a standalone test
https://doi.org/10.3390/jcm14217748
#MondayTip
#Collaterals
Collateral status are relevant in stroke
π§ Good collaterals + recanalization β strong outcomes
β οΈ Poor collaterals β limited benefit, even if opened
CTA isnβt just diagnosticβitβs decision-making
https://doi.org/10.3174/ajnr.a3817
#MondayTip
Cancer-related stroke β routine ESUS
~50% of strokes in active cancer are cryptogenic, but many are cancer-driven hypercoagulable events
π14β29% recur at 1 year
βοΈAnticoag vs aspirin? Still equipoise
π§ Classify. Risk-stratify. Individualize
https://doi.org/10.1161/str.0000000000000517
#MondayTip
Hypoperfusion Intensity Ratio
#HIR may be the most practical collateral biomarker in AIS
β¬οΈHigh HIR (>0.4) β rapid core growth, β hemorrhage risk, worse mRS.
β¬οΈLow HIR β robust collaterals & better EVT outcomes.
https://doi.org/10.3174/ajnr.A8557
Missed what happened in February at @WorldStrokeEd? π
Catch up with our monthly newsletter!
π Upcoming & past webinars
ποΈ New podcast episodes
π Fresh infographics
π‘ Latest #MondayTips by @interneurona
π€ Read it here:
https://www.world-stroke-academy.org/news/february-newsletter-3/
#StrokeEducation #StrokeCare
#MondayTip
Not all βseizuresβ are epilepsy.
π§ #LimbShakingTIA = hypoperfusion from carotid disease
π Triggered by standing/exertion
π EEG often normal
β οΈ Treat flow, not firing
https://doi.org/10.1136/pn-2025-004976
#MondayTip
New AHA dyslipidemia guides emphasizes earlier &β intensive LDL-Cβ¬οΈ, often requiring non-statin therapy
PCSK9 options:
π§¬Inclisiran (siRNA):βPCSK9 production, dosing every 6m
πAlirocumab/Evolocumab:βcirculating PCSK9
Both βLDL~50β60%, including in stroke patients
Missed what happened in February at @WorldStrokeEd? π
Catch up with our monthly newsletter!
π Upcoming & past webinars
ποΈ New podcast episodes
π Fresh infographics
π‘ Latest #MondayTips by @interneurona
π€ Read it here:
https://www.world-stroke-academy.org/news/february-newsletter-3/
#StrokeEducation #StrokeCare
#MondayTip
#Stroke is not the same in #women and men
βοΈWomen have unique risk factors (pregnancy complications, menopause), are more likely to be misdiagnosed, rec&eive thrombolysis less often, despite similar benefit
Time for sex-responsive stroke care
https://doi.org/10.1177/17474930251393009
#MondayTip
Hypoperfusion Intensity Ratio
#HIR may be the most practical collateral biomarker in AIS
β¬οΈHigh HIR (>0.4) β rapid core growth, β hemorrhage risk, worse mRS.
β¬οΈLow HIR β robust collaterals & better EVT outcomes.
https://doi.org/10.3174/ajnr.A8557
#MondayTip
Cancer-related stroke β routine ESUS
~50% of strokes in active cancer are cryptogenic, but many are cancer-driven hypercoagulable events
π14β29% recur at 1 year
βοΈAnticoag vs aspirin? Still equipoise
π§ Classify. Risk-stratify. Individualize
https://doi.org/10.1161/str.0000000000000517
#MondayTip
Cancer-related stroke β routine ESUS
~50% of strokes in active cancer are cryptogenic, but many are cancer-driven hypercoagulable events
π14β29% recur at 1 year
βοΈAnticoag vs aspirin? Still equipoise
π§ Classify. Risk-stratify. Individualize
https://doi.org/10.1161/str.0000000000000517
May #PaperofTheMonth: πππππππ-ππππππ: π
ππππ¨π« πππ ππ§π‘π’ππ’ππ’π¨π§ ππππ©π¬ π’π§ππ¨ ππππ¨π§πππ«π² πππ«π¨π€π ππ«ππ―ππ§ππ’π¨π§
π€Commentary
π½#MondayTip
π§4 expert interview episodes
Access it: https://www.world-stroke-academy.org/news/the-paper-of-the-month-may-4/
#StrokeEducation
πFollowing #WorldHypertensionDay, we are pleased to invite you to our upcoming webinar on ππ²π©ππ«πππ§π¬π’π¨π§ ππ§π ππ§ππ«ππππ«πππ«ππ₯ πππ¦π¨π«π«π‘ππ π
ποΈJune 24th, 2-3pm (CEST)
https://l1nq.com/n59h38h
π€@WorldStrokeOrg @WorldHyperLeag @GeorgeMedicines
π’ Still time to register for the #ESOC2026 Highlights Webinar to explore the most important advances in #stroke research & care.
Organised by @American_Stroke, ESO & @WorldStrokeOrg
πhttps://ow.ly/gZ7950YR0Sk
@American_Heart @FishingNeurons @bijoymenon @sheilambrasil @SposatoL
π’ Join the #ESOC2026 Highlights Webinar on 21 May, to explore the most important advances in #stroke research &clinical care.
Organised by @American_Stroke, ESO & @WorldStrokeOrg
πhttps://ow.ly/gZ7950YR0Sk
@American_Heart @FishingNeurons @bijoymenon @sheilambrasil @SposatoL
